My current projects include 1) accurate volumetric measurements of radiation doses using radiochromic gel dosimeters and optical CT scanners, 2) evaluating a non-invasive immobilization technique for stereotactic radiosurgery (SRS) and 3) implementing a photodynamic therapy (PDT) clinical program for treating superficial skin cancer. 1) To assure the quality of advanced 3D radiation cancer treatment planning software and dose delivery hardware, it is important that the spatial distribution of ionizing radiation deposited within the exposed tissues be accurately and precisely mapped out. I am interested in investigating the optimal optical CT scanner light source and geometry for quantitatively reading the dose in 3D that is “written” into a radiochromic gel during a setup that emulates patient treatment conditions. 2) The reliable immobilization and target localization accuracy of frame-based SRS have established the technique as a gold standard, but it is associated with significant disadvantages including stress on the patient, and the need to simulate, plan and treat patients all in the same day. My interest lies in evaluating commercially available non-invasive immobilization systems that overcome frame-based limitations. By doing an inter-comparison of their respective positional accuracies, my research goal is to determine which system offers the highest degree of immobilization and ease of use for SRS patients. 3) One type of PDT is used to destroy non-melanoma superficial skin cancers. Some patients receiving this therapy are ones who have already received conventional treatments and have not had much success. Photosensitive compounds in the form of a topical cream are applied and selectively up taken by the cancerous cells. Subsequent illumination with red light results in lethal cell damage. My research interest lies in better understanding what physical measurements are needed to predict the response of individual patients to PDT and to optimize their treatment. Ultimately the goal will be to increase the clinical utilization of this mode of skin cancer therapy.
Steven Babic BSc, MSc, PhD
T: (416) 480-6100
Carlo Fidani Peel Regional Cancer Centre - Credit Valley Hospital
2200 Eglinton Ave W.
Mississauga, ON, L5M 7S4
Please contact Faculty Member for more information
Ph.D., Medical Biophysics, Department of Medical Biophysics, Western University
M.Sc., Physics, Department of Physics, Queen’s University
B.Sc.(Hons.), Medical and Health Physics, Department of Physics, McMaster University
Deputy Head and Medical Physicist, Department of Medical Physics, Odette Cancer Centre – Sunnybrook Health Sciences Centre,
Assistant Professor, Department of Radiation Oncology, University of Toronto