Richard HillPhD
Professor

Contact Info

T. (416) 581-7861
F. (416) 946-2984

Location

Princess Margaret Cancer Centre
610 University Avenue
Toronto
ON, M5G 2M9

Clinical Interests

Hypoxia; www.uhnresearch.ca/hypoxia

Accepting

Please contact Faculty Member for more information

Degree/Qualifications

BA, Physics, St. John’s College, Oxford, England
PhD, Radiation Biology, Medical College of St. Bartholemew’s Hospital, London, England

Appointments

Professor, Department of Radiation Oncology, University of Toronto
Professor, Department of Medical Biophysics, University of Toronto
Senior Scientist, Experimental Therapeutics, Ontario Cancer Institute

Research/Teaching

Research Synopsis:

  • Clinical and experimental studies of tumour hypoxia
  • Radiation effects on wound healing
  • Response of lung to partial volume irradiation
  • Effects of exposure to hypoxia on metastatic potential of tumour cells

Publications and Awards

Recent Publications

Clarkson, R., Lindsay, P.E., Ansell, S., Wilson, G., Jelveh, S., Hill, R.P., Jaffray, D.A. Characterization of image quality and image-guidance performance of a preclinical microirradiator. Med Phys. 38(2):845-56, Feb 2011.

Rosenthal, R.A., Fish, B., Hill, R.P., Huffman, K.D., Lazarova, Z., Mahmood, J., Medhora, M., Molthen, R., Moulder, J.E., Sonis, S.T., Tofilon, P.J., Doctrow, S.T. Salen Mn complexes mitigate radiation injury in normal tissues. Anticancer Agents Med Chem. 11(4):359-72, May 2011

Zaugg, K., Yao, Y., Reilly, P,T., Kannan, K., Kiarash, R., Mason, J., Huang, P., Sawyer, S.K., Fuerth, B., Faubert, B., Kalliomaki, T., Elia, A., Luo, X., Nadeem, V., Bungard, D., Yalavarthi, S., Growney, J.D., Wakeham, A., Moolani, Y., Silvester, J., Ten, A.Y., Bakker, W., Tsuchihara, K., Berger, S.L., Hill, R.P., Jones, R.G., Tsao, M., Robinson, M.O., Thompson, C.B., Pan, G., Mak, T.W. Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes Dev. 25(10):1041-51, May 2011

Chaudary, N., Hedley, D.W., Hill, R.P. Orthotopic xenograft model of cervical cancer for studying microenvironmental effects on metastasis formation and response to drug treatment. Curr Protoc Pharmacol. Chapter 14:Unit 14.19, June 2011.

Mahmood, J., Jelveh, S., Calveley, V., Zaidi, A., Doctrow, S.R.,Hill, R.P. Mitigation of radiation-induced lung injury by genistein and EUK-207. Int J Radiat Biol. 87(8):889-901, Aug 2011

Kasper, P., Chen, R., Hyrien, O., Jelveh, S., Bristow, R.G., Hill, R.P. Biodosimetry using radiation-induced micronuclei in skin fibroblasts. Int J Radiat Biol. 87(8) 824-38, Aug 2011

Hill, R.P., Zaidi, A., Mahmood, J., Jelveh, S.. Investigations into the role of inflammation in normal issue response to irradiation. Radiother Oncol. 101(1):73-9, Oct 2011

Chaudary, N., Pintilie, M., Hedley, D., Fyles, A.W., Milosevic, M., Clarke, B., Hill, R.P., Mackay, H. Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation. Cancer. [Epub ahead of print] Oct 2011

Chaudary, N., Milosevic, M., Hill, R.P. Suppression of vascular endothelial growth factor receptor 3 (VEGFR3) and vascular endothelial growth factor C (VEGFC) inhibits hypoxia-induced lymph node metastases in cervix cancer. Gynecol Oncol. 123(2):393:400, Nov 2011

Mahmood, J., Jelveh, S., Calveley, V., Zaidi, A., Doctrow, S.R.,Hill, R.P. Mitigation of lung injury after accidental exposure to radiation. Radiat Res.176(6):770-80, Dec 2011

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