James BrierleyMS, MB, FRCR, FRCPC

Contact Info

T. (416) 946-2124
F. (416) 946-6566


Princess Margaret Cancer Centre
610 University Avenue
ON, M5G 2M9

Clinical Interests

Management of tumours of the thyroid, pituitary and the gastrointestinal tract, Cancer staging


Please contact Faculty Member for more information


BSc, London University
MS, London University
MB, London University
FRCP, Fellow Royal College of Physicians
FRCR, Royal College of Radiologists
FRCPC, Radiation Oncology


Professor, Department of Radiation Oncology, University of Toronto
Staff physician, Department of Radiation Oncology, Princess Margaret Hospital/University Health Network


Research Synopsis:

  • Assessing the role of concurrent chemoradiation in anal and rectal cancer
  • Determining the value of external beam radiation therapy in thyroid cancer

Publications and Awards

Recent Publications

Brierley J, Tsang R, Panzarella, Bana N. Prognostic Factors and the Effect of Treatment with Radioactive Iodine and External Beam Radiation on Patients with Differentiated thyroid cancer seen at a single institution over forty years. Clin Endocrinol (Oxf) 63:418-427, 2005.

Wang Y, Cummings B, Catton, P, Dawson L, Kim J, Ringash J, Wong R, Yi Q-L, Brierley J. Primary Radical External Beam Radiotherapy of Rectal Adenocarcinoma: Long Term Outcome of 271 patients. Radiother Oncol. 77(2):126-32. 2005.

Brierley J. The evolving TNM cancer staging system: an essential component of cancer care. CMAJ; 174:155-6. 2006

Wiltshire KL, Ward IG, Swallow C. Oza AM, Cummings B, Pond GR, Catton P, Kim J, Ringash J, Wong CS, Wong R, Siu LL, Moore M, Brierley J. Preoperative radiation with concurrent chemotherapy for resectable rectal cancer: Effect of dose escalation on pathologic complete response, local recurrence-free survival, disease-free survival, and overall survival. Int J Radiat Oncol Biol Phys., 1:64(3): 709-16. 2006.

Brierley J, Tsang RW. External Beam Radiotherapy of Thyroid Cancer. For publication in Endocrinology and Metabolism Clinics of North America: 37: 497-509. 2008

Sawka AM, Brierley JD, Tsang RW, Thabane L, Rotstein L, Gafni A, Straus S, Goldstein DP An updated systematic review and commentary examining the effectiveness of radioactive iodine remnant ablation in well-differentiated thyroid cancer.Endocrinology and Metabolism Clinics of North America: 37: 457-480 2008.

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