Fei-Fei Liu MD, FRCPC
Professor

Contact Info

T: (416) 946-2123
F: (416) 946-2038
Website

Location

Princess Margaret Cancer Centre
610 University Avenue
Toronto, ON, M5G 2M9

Accepting

Please contact Faculty Member for more information

Degree/Qualification

MD, University of Toronto
FRCPC, Radiation Oncology

Appointments

Professor & Chair, Department of Radiation Oncology, University of Toronto
Professor, Department of Medical Biophysics, University of Toronto
Professor, Department of Otolaryngology, University of Toronto
Staff Radiation Oncologist, Princess Margaret Hospital/University Health Network
Senior Scientist, Ontario Cancer Institute
Dr. Mariano A. Elia Chair in Head and Neck Cancer Research

Clinical Interests

Breast cancer, Head and neck cancer

Research/Teaching

Research Synopsis

  • Novel molecular therapies & HTS: With the discovery of UROD as a novel radiosensitizing target, our lab is now expending a significant effort in trying to develop a small molecule inhibitor of this enzyme. This work is supported by a CIHR Proof-of-Principle grant, in collaboration with a porphyrin chemist based at the University of Texas – Austin. Other “hits” identified from the original screen are also currently undergoing secondary validation for future explorations.
  • Molecular Predictors of Breast, Cervix, and Head & Neck Cancers: We are currently determining the biological mechanisms underpinning the differential clinical outcome between HPV-positive vs. HPV-negative oropharyngeal CAs (OPC). We are also conducting global micro-RNA (miR) profilings on human cervix, and nasopharyngeal carcinomas to both identify potential predictive signatures, and also to better understand mechanisms of cancer progression.
  • Additional information is available on our Liu Lab website.

 

Publications and Awards

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