Fei-Fei LiuMD, FRCPC
Princess Margaret Cancer Centre
610 University Avenue
ON, M5G 2M9
Clinical InterestsBreast cancer, Head and neck cancer
AcceptingPlease contact Faculty Member for more information
MD, University of Toronto
FRCPC, Radiation Oncology
Professor & Chair, Department of Radiation Oncology, University of Toronto
Professor, Department of Medical Biophysics, University of Toronto
Professor, Department of Otolaryngology, University of Toronto
Staff Radiation Oncologist, Princess Margaret Hospital/University Health Network
Senior Scientist, Ontario Cancer Institute
Dr. Mariano A. Elia Chair in Head and Neck Cancer Research
- Novel molecular therapies & HTS: With the discovery of UROD as a novel radiosensitizing target, our lab is now expending a significant effort in trying to develop a small molecule inhibitor of this enzyme. This work is supported by a CIHR Proof-of-Principle grant, in collaboration with a porphyrin chemist based at the University of Texas – Austin. Other “hits” identified from the original screen are also currently undergoing secondary validation for future explorations.
- Molecular Predictors of Breast, Cervix, and Head & Neck Cancers: We are currently determining the biological mechanisms underpinning the differential clinical outcome between HPV-positive vs. HPV-negative oropharyngeal CAs (OPC). We are also conducting global micro-RNA (miR) profilings on human cervix, and nasopharyngeal carcinomas to both identify potential predictive signatures, and also to better understand mechanisms of cancer progression.
- Additional information is available on our Liu Lab website.